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Laryngopedia

To educate about voice, swallowing, airway, coughing, and other head and neck disorders

Laryngopedia By Bastian Medical Media

Multimedia Encyclopedia


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Wegener’s Granulomatosis

A rare inflammatory disease of small arteries and veins (vasculitis) that classically involves vessels supplying the tissues of the lungs, nasal passages (sinuses), and kidneys. At our practice, we see a large population of individuals with what we believe to be a forme fruste (incomplete expression) of Wegener’s granulomatosis* causing subglottic and tracheal stenosis.

*Newer terminology is granulomatosis with polyangiitis (GPA)


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Wegener’s Granulomatosis*: Forme Fruste (incomplete expression)
Wegener’s granulomatosis is a rare autoimmune disorder in which blood vessels become inflamed. The inflammation causes swelling and scarring. Three typical organs attacked are sinus/nasal cavities, lungs, and kidneys. In the forme fruste variant, it is mostly an inflammatory stenosis (narrowing) of the area below the vocal folds, and also the trachea. A person becomes short of breath and begins to make harsh breathing sounds due to the narrowed passageway. This is an example of one means of management: dilation of the narrowed area during a very brief general anesthetic in an outpatient operating room.


Working Diagnosis

Working diagnosis is a term used to refer to the leading contender in a list of two or more potential diagnoses. Infrequently, at the conclusion of the initial consultation, we have two fairly strong diagnostic possibilities, and begin with treatment for one of them, now termed the working diagnosis, as the next step in finalizing a diagnosis. If a working diagnosis is relatively certain, we may begin treatment for that diagnosis. In other cases, additional testing is in order to try to solidify the working diagnosis into a final diagnosis.

See also differential diagnosis.



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