An encyclopedia about voice, swallowing, airway, coughing, & other head + neck disorders.

Exercise Intolerance

Exercise intolerance is an inability to participate in any significant level of aerobic activity without becoming unacceptably short of breath. When this is the result of airway disturbance (as opposed to heart or lung disease), the individual may make involuntary breathing noises, such as stridor, or involuntary inspiratory phonation.

Progressive Radiation Fibrosis Effects on the Larynx and a Solution to some of It

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Forty years post-radiation (1 of 8)

This photo is taken forty years after curative radiation for a vocal cord cancer. Four decades of progressive radiation fibrosis (“leatherization”) has taken away arytenoid movement so that this is the maximum opening. The patient is exercise-intolerant and makes loud inspiratory breathing noises while sleeping. Her voice is also very poor.

Involuntary inspiratory voice (2 of 8)

With sudden inspiration, the darker mucosa (at the arrows) indraws and vibrates, making an involuntary inspiratory voice.

Only capable of high pitch (3 of 8)

Other than a stage whisper, she can only make a very high pitch, because the only mucosa capable of vibration is the small segment indicated by the arrows.

Open phase vibration (4 of 8)

Again under strobe light, this is the open phase of vibration, with arrows again indicating the short segment of mucosa that can oscillate.

One week post-commissuroplasty (5 of 8)

A week after posterior commissuroplasty, the patient’s breathing is much improved. Despite the distant view, the “cookie bites” taken from the posterior cords are visible.

Rapid inhalation, closer view (6 of 8)

In a much closer view, the posterior vocal cord divots are seen well. The segment of flexible mucosa is indrawing here as the patient inhales rapidly (at arrows).

Three months post-surgery (7 of 8)

Three months after the laser surgery, the patient continues to say the improvement of breathing is “large.” In this distant view the full reason why is not seen.

Closer view, post-surgery (8 of 8)

In a closer view, as is always the case after complete healing, the divots are smaller than just after surgery.

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