Sarcoma
A sarcoma is a malignant tumor that originates in mesenchymal tissue. Mesenchymal tissue comprises muscle, bone, fat, connective tissue, blood vessels, and cartilage. If, instead, a malignancy originates in lining or covering tissues—which includes skin, bronchial tubes, the lining of the mouth, throat, and gastrointestinal tract, and breast and salivary gland ducts—then that tumor is called a carcinoma.
Carcinoma Vs. Sarcoma
Carcinomas are far more common than sarcomas, and sarcomas involving the larynx are rare, with chondrosarcoma (“chondro-” refers to cartilage origin) heading the list. The clinicians at our laryngology practice have seen hundreds of carcinomas in their career, but probably no more than 20 sarcomas.
Sarcoma in the Larynx
Sarcoma (1 of 2)
Sarcoma (2 of 2)
Resources for Further Reading
Velez M, Ernesto Martinez Duarte, Diaz-Perez JA, et al. Primary Sarcomas of the Larynx: A Clinicopathologic Study of 27 Cases. Head and Neck Pathology. 2021;15(3):905-916. doi:10.1007/s12105-021-01314-8
Mantilla JG, Xu H, Ricciotti RW. Primary Sarcomas of the Larynx: A Single Institutional Experience with Ten Cases. Head and Neck Pathology. 2019;14(3):707-714. doi:10.1007/s12105-019-01106-1
1.Dei AP, Raf Sciot, Giannini C, et al. Synovial Sarcoma of the Larynx and Hypopharynx. The Annals of otology, rhinology & laryngology. 1998;107(12):1080-1085. doi:10.1177/000348949810701215
AbdullGaffar B, Keloth T. Laryngeal sarcomas: A case series of 5 cases. Annals of Diagnostic Pathology. 2018;37:35-41. doi:10.1016/j.anndiagpath.2018.09.007
Khosla D, Budhi Singh Yadav, Kumar R, et al. Low-grade myofibroblastic sarcoma of the larynx: A rare entity with review of literature. Journal of Cancer Research and Therapeutics. 2013;9(2):284-284. doi:10.4103/0973-1482.113387
Maroun CA, Khalifeh I, A. Tfayli, R.V. Moukarbel. Primary Ewing Sarcoma of the Larynx with Distant Metastasis: A Case Report and Review of the Literature. Current Oncology. 2019;26(4):574-577. doi:10.3747/co.26.5001
Dwyer GK. Fibrosarcoma of the Larynx. Archives of Otolaryngology – Head and Neck Surgery. 1953;58(4):442-443. doi:10.1001/archotol.1953.00710040464008
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